Proteins in Action: Monitored by tr(time-resolved) FTIR spectroscopy

In the Postgenom era one of the remaining major challenges is the detailed understanding of protein networks within the living cell. Currently, there is a large gap between the detailed understanding of proteins in vitro and their description in interaction pathway maps in systems biology. In order to contribute to a more detailed understanding of protein interactions a combined approach of x-ray structure analysis, time-resolved FTIR spectroscopy, Molecular Dynamic and QM/MM biomolecular simulations is used.